What We Do

Engineered to protect 
what matters most.

We design, manufacture, install and support pharmaceutical isolators for hospital pharmacy and nuclear medicine departments. Validated to the highest regulatory standards. Backed by a service partnership that lasts the lifetime of the product.

Why Choose Cirrus?

Built around your
team. Backed by ours.

From first conversation to long-term support, everything is handled by the people who know your system best.

Services

Support that continues long after installation.

Installing your isolator is the beginning of the relationship, not the end of it. Every Cirrus system is supported by our UK-based service team - the same people who designed and built it.

About Cirrus

Specialist by design.

Founded in 2013 by engineers who believed pharmaceutical isolators could be better - better designed, better built and better supported. Today, Cirrus systems operate across seven countries and three continents.

Pharmaceutical Isolators

ALTO Pharmacy Isolators

The ALTO is Cirrus's flagship pharmaceutical isolator. Available in 2-glove and 4-glove configurations, with positive or negative pressure and a choice of True Flow unidirectional or turbulent airflow – specified to your environment from the outset.

Built to EC GMP Grade A standards. Designed around the people who use it every day.

Applications

One system. 
A wide range of pharmacy applications.

ALTO can be specified for the demands of modern aseptic pharmacy, supporting critical preparation workflows with the right containment, airflow and configuration from the outset.

EC GMP Grade A throughout.

True Flow unidirectional airflow - engineered to maintain Grade A conditions across the full work zone.

Designed for the operator.

Variable height base-frame, integrated footrest and reachable internal surfaces.

Remote diagnostic capability.

Connected support to identify and often resolve issues without an on-site visit.

Automatic leak testing.

Automatic glove integrity testing, pre-set to run out of hours.

Battery backup.

UPS maintains key functions during power interruption.

Full validation package.

FAT, IQ, SAT and OQ documentation supplied and completed at commissioning.

Customisation Options

Configured around your workflow.

Tailor your isolator to the way you work. Our modular options integrate seamlessly so you can improve accuracy, maintain compliance and stay in control.

With increasing focus on decontamination requirements under Annex 1, VHP gassing capability is becoming an essential consideration for many pharmacy environments.

The ALTO VHP integrates validated VHP decontamination directly into the isolator platform - designed for routine chamber decontamination in line with current GMP and Annex 1 guidance. It is available as a factory-integrated solution on new builds, or as a retrofit to existing ALTO units already in the field.

Gassing configuration is treated as a consultative process. We work with a number of established VHP technology suppliers and will recommend the right partner for your application, workflow, and budget.

For higher throughput environments requiring rapid ingress decontamination, see our ALTO VHP Rapid Gassing Isolator.

Pharmaceutical Isolators

ALTO VHP Rapid Gassing Isolator

The ALTO VHP Rapid Gassing Isolator is our answer to rapid gassing requirements. Designed for high-throughput environments, it is built on the same platform as the ALTO - with one critical difference: a larger rapid gassing hatch. 

The Rapid Gassing Isolator provides the ingress hatch with a full, rapid decontamination cycle on products being moved into the process chamber, allowing fast, continuous throughput without interrupting the work session.

Where a full isolator decontamination cycle is required, this can be completed separately — typically out of hours.
We work with a number of established gassing suppliers on integrated rapid gassing solutions, for high-throughput pharmacy environments where speed and sterility assurance are both non-negotiable.

Applications

One system. 
Built around your pharmacy.

ALTO can be configured for the way your team works - from cytotoxic preparation and TPN compounding to CIVAS and high-throughput services. The right containment, airflow and layout, designed in from the outset.

Rapid ingress decontamination.

A dedicated rapid gassing hatch delivers a full VHP decontamination cycle on product entering the process chamber - without interrupting the work session.

Built for high throughput.

Designed for environments where frequent decontamination cycles are operationally critical. Fast turnaround, continuous workflow.

Full isolator decontamination when needed.

A complete chamber decontamination cycle can be run separately — typically out of hours - without compromising daytime productivity.

Built to the same standard as the ALTO.

Same 3mm 316 stainless steel construction, EU14 HEPA filtration, True Flow airflow, and full control system — with rapid gassing capability built in from the outset.

GMP and Annex 1 compliant.

Validated decontamination performance. Full documentation package included.

Full validation package.

FAT, IQ, SAT and OQ documentation supplied and completed at commissioning.

Pharmaceutical Isolators

ALTO VHP Dual Rapid Gassing Isolator

The ALTO VHP Dual Rapid Gassing Isolator is purpose-built for the highest throughput pharmacy environments. Featuring dual process chambers served by a single shared rapid gassing ingress, it delivers continuous, validated product decontamination without interrupting the work session - maintaining maximum output across both chambers simultaneously.

Designed for hub and spoke manufacturing models, pathfinder projects, and any facility where throughput and sterility assurance are both non-negotiable.

Speak to our team to find out more.

Applications

One system. 
Built around your pharmacy.

ALTO can be configured for the way your team works - from cytotoxic preparation and TPN compounding to CIVAS and high-throughput services. The right containment, airflow and layout, designed in from the outset.

Maximum throughput.

Two process chambers sharing one rapid gassing ingress — double the capacity, same fast decontamination cycle.

Continuous flow.

Product is decontaminated as it enters the system. No interruption to the work session, no waiting between cycles.

Full isolator decontamination when needed.

A complete chamber decontamination cycle can be run separately — typically out of hours - without compromising daytime productivity.

Built to the same standard as the ALTO.

Same 3mm 316 stainless steel construction, EU14 HEPA filtration, True Flow airflow, and full control system — with rapid gassing capability built in from the outset.

GMP and Annex 1 compliant.

Validated decontamination performance. Full documentation package included.

Full validation package.

FAT completed prior to dispatch. IQ, SAT, and OQ documentation supplied and completed at commissioning.

Pharmaceutical Isolators

Bespoke Systems

Not every application fits a standard configuration. Where your requirements fall outside our core range, our in-house team can design and build a solution from the ground up - to your specification, your environment, and your regulatory requirements.

Every bespoke project begins with a conversation. There's no obligation - just an open discussion about what you need and whether we can help.

What we can do.

Our in-house capability spans mechanical design, software development, and control systems. If you have a containment challenge, bring it to us.

Our approach.

Bespoke projects follow the same rigorous process as our standard range — URS review, Design Qualification sign-off before manufacture begins, full FAT prior to dispatch, and complete validation documentation at handover.

Nuclear Medicine Systems

TC99m INCUS

The INCUS is a purpose-built shielded isolator for Tc-99m generator elution in nuclear medicine departments. Designed to protect operators and the environment without compromising workflow, it combines lead-equivalent shielding, lead glass viewing panels, and negative pressure containment in a system built on the same proven platform as our ALTO pharmaceutical isolator range.

Every INCUS is configured to your department's specific requirements — generator capacity, glove port configuration, and dose calibrator integration are all agreed as part of the specification process.

Applications

Built for nuclear medicine. 
Configured around your workflow.

INCUS provides the shielding, containment and clear visibility needed for safe, efficient Tc-99m generator elution. Each system is configured around your department - from generator capacity and glove port layout to dose calibrator integration — so protection never comes at the expense of workflow.

Operator & environmental protection.

Negative pressure containment, lead-equivalent shielding, and lead glass viewing panels - engineered to protect operators and the environment throughout every procedure.

Dose calibrator integration.

Integrated as standard. We work with a range of compatible supplier models to ensure the right fit for your department.

Built on a proven platform.

The INCUS shares its core architecture with the ALTO - the same 3mm 316 stainless steel construction, EU14 HEPA filtration, HMI touchscreen control system, and in-house software. Familiar, reliable, and fully supported.

Flexible configuration.

Available with 2, 3, or 4 glove process modules. Standard 2-generator elution module, with 4-generator capacity available.

Remote diagnostics capability.

When connected to the facility network, issues can be identified and often resolved without an on-site visit - minimising downtime in a critical clinical environment.

Full validation package.

FAT completed prior to dispatch. IQ, SAT, and OQ documentation supplied and completed at commissioning.

Require More Throughput?

INCUS Dual.

For departments requiring higher throughput or dual generator capacity, the INCUS Dual features two process chambers - accommodating up to 4 Tc-99m generators across both elution modules.

Available in 2+2, 3+3, and 4+4 glove configurations. Speak to our team to discuss whether the Dual configuration is right for your department.

Nuclear Medicine Systems

STRATUS Blood Labelling Isolator.

The STRATUS is a shielded isolator designed for blood radiolabelling procedures in nuclear medicine departments. Built on the same platform as the INCUS, it features an integrated centrifuge - developed in-house and engineered to minimise vibration and integrate seamlessly into the process chamber.

Like the INCUS, the STRATUS operates under negative pressure with lead-equivalent shielding and lead glass viewing panels, providing full operator and environmental protection throughout every procedure.

Application

Designed around one critical feature.

STRATUS is purpose-built for blood radiolabelling in nuclear medicine and radio-pharmacy departments. Its integrated centrifuge keeps a key part of the process within the shielded, negative-pressure chamber - helping teams work safely, efficiently and with clear visibility throughout.

Operator & environmental protection.

Negative pressure containment, lead-equivalent shielding, and lead glass viewing panels - engineered to protect operators and the environment throughout every procedure.

Integrated centrifuge.

Developed in-house and engineered to minimise vibration, the centrifuge integrates seamlessly into the process chamber without compromising the working environment or sterility assurance.

Built on a proven platform.

The STRATUS shares its core architecture with the INCUS and ALTO -the same 3mm 316 stainless steel construction, EU14 HEPA filtration, HMI touchscreen control system, and in-house software.

Flexible configuration.

Available with 2, 3, or 4 glove process modules - configured to your department's workflow from the outset.

Remote diagnostics capability.

When connected to the facility network, issues can be identified and often resolved without an on-site visit - minimising downtime in a critical clinical environment.

Full validation package.

FAT completed prior to dispatch. IQ, SAT, and OQ documentation supplied and completed at commissioning.

Nuclear Medicine Systems

Combine INCUS & STRATUS

The Combined INCUS & STRATUS brings Tc-99m generator elution and blood radiolabelling capability together in a single shielded isolator - eliminating the need for two separate units and reducing the footprint required in the nuclear medicine department.

The system features an integrated elution module with automated generator raise mechanism, and a process chamber with integrated centrifuge - all operating under negative pressure with lead-equivalent shielding and lead glass viewing panels.

Application

One shielded system.
Two essential workflows.

The combined INCUS & STRATUS brings Tc-99m generator elution and blood radiolabelling together in one purpose-built isolator — reducing the footprint, handovers and duplication associated with separate units.

An integrated elution module, automated generator raise mechanism and centrifuge sit within a single negative-pressure process chamber, protected by lead-equivalent shielding and lead-glass viewing panels. It is a more streamlined way to support the full workflow without compromising operator protection or visibility.

Two capabilities - one unit.

Elution and blood radiolabelling in a single shielded isolator - reducing footprint, simplifying workflow, and eliminating the need for two separate systems.

Automated generator raise mechanism.

Tc-99m generators are stored in a shielded space beneath the elution module and raise automatically when the radioisotope needs drawing up - minimising manual handling and operator exposure.

Integrated centrifuge.

Developed in-house and engineered to minimise vibration, the centrifuge integrates seamlessly into the process chamber without compromising the working environment or sterility assurance.

Operator and environment protection.

Negative pressure containment, lead-equivalent shielding, and lead glass viewing panels — engineered to protect operators and the environment throughout every procedure.

Built on a proven platform.

Shares its core architecture with the INCUS and ALTO - the same 3mm 316 stainless steel construction, EU14 HEPA filtration, HMI touchscreen control system, and in-house software.

Remote diagnostics capability.

When connected to the facility network, issues can be identified and often resolved without an on-site visit - minimising downtime in a critical clinical environment.

Full validation package.

FAT completed prior to dispatch. IQ, SAT, and OQ documentation supplied and completed at commissioning.

Our Values

Build around people.
Driven by better.

From the first conversation to long-term support, our values shape how we design, build and stand behind every Cirrus system.

Team / Facilities

The people and place behind every system.

Our team handles every stage of your project — from initial specification through to installation and aftercare. The people who design your isolator are the same people who build it, deliver it, and support it.

Our manufacturing facility is based in Buckinghamshire, where every Cirrus isolator is designed, built, and tested before it leaves our doors.